EUTECNIQ Sciences

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Scientific insights Primary data Published evidence Educational models

Models, data and methods for botanical science, each labeled by the kind of evidence behind it

Calculators, datasets and methods articles, grouped by discipline. Labels separate published measurements and regulations from proposals and simulations.

18pages in the library
176figures and diagrams
117interactive tools
343evidence labels
752registered claims

Status. EUTECNIQ Sciences is a company in formation. It has no laboratory, no measured results and no customers yet.

Library map

Six groups of pages: select a group to zoom, a page to open it

The insights library: groups inside, pages outsideSite structure
Built from the site navigation; tooltips give each page's figure and tool counts. The links above lead to related pages in other sections.
Evidence labels

Ten labels separate what is measured, published or required from what is proposed or simulated

What each page rests on: share of its evidence labels by kind; select a column to sortCounted at build time
Every evidence label printed on each page, counted when the site is built and grouped into six kinds. Darker cells mean a larger share.
Data table
Evidence labels on each library page, by family, counted at build time
PageLabelsVerified dataPeer-reviewedRegulation or guidanceThird-party estimateProposal, partner or riskSimulation or schematic
Interactive science lab101 (10%)1 (10%)0 (0%)0 (0%)0 (0%)8 (80%)
Thermodynamics & COSMO-SAC2810 (36%)4 (14%)0 (0%)0 (0%)0 (0%)14 (50%)
Quantum chemistry243 (12%)4 (17%)0 (0%)0 (0%)3 (12%)14 (58%)
Ab initio reactivity210 (0%)5 (24%)0 (0%)0 (0%)2 (10%)14 (67%)
Design space & optimization180 (0%)6 (33%)0 (0%)0 (0%)2 (11%)10 (56%)
Large Botanical Model338 (24%)6 (18%)0 (0%)0 (0%)13 (39%)6 (18%)
Botanical Intelligence214 (19%)2 (10%)0 (0%)0 (0%)11 (52%)4 (19%)
Evidence & pharmacokinetics211 (5%)10 (48%)3 (14%)1 (5%)4 (19%)2 (10%)
Combination science & synergy111 (9%)5 (45%)0 (0%)0 (0%)1 (9%)4 (36%)
Lessons learned137 (54%)4 (31%)1 (8%)0 (0%)0 (0%)1 (8%)
Operational excellence3010 (33%)5 (17%)0 (0%)0 (0%)0 (0%)15 (50%)
Sustainability and LCA175 (29%)5 (29%)4 (24%)2 (12%)0 (0%)1 (6%)
Market data259 (36%)1 (4%)0 (0%)14 (56%)0 (0%)1 (4%)
Competitive landscape2113 (62%)0 (0%)1 (5%)0 (0%)7 (33%)0 (0%)
Global botanical atlas176 (35%)4 (24%)1 (6%)1 (6%)5 (29%)0 (0%)
Global trade data1813 (72%)2 (11%)0 (0%)0 (0%)3 (17%)0 (0%)
Model register21 (50%)0 (0%)0 (0%)0 (0%)0 (0%)1 (50%)
Sources & methodology132 (15%)2 (15%)3 (23%)1 (8%)4 (31%)1 (8%)

There is no label for verified EUTECNIQ experimental results because none exist yet.

Explanation, details and sources: the ten labels
LabelMeaningHow to read it
Verified factVerified fact or government data from a primary sourceChecked against the original record (for example NIST, FDA, UN Comtrade); dated where it can change.
Peer-reviewedEstablished published evidenceComes from a peer-reviewed paper or standard reference work; cited with its DOI.
Regulatory requirementStatute or regulationBinding text, such as the FD&C Act or 21 CFR, cited to the section and dated.
Agency guidanceFDA or other agency guidanceA non-binding recommendation; marked final or draft, with its date.
Third-party estimateMarket research and other estimatesSomeone else's estimate, reported with its definitions and scope; not verified by EUTECNIQ.
Founder-reportedThe founder's prior experienceA result achieved at a prior employer and reported by the founder; it belongs to that employer, not to EUTECNIQ.
ProposalManagement proposal or planSomething EUTECNIQ would do; it has not been built or done.
SimulationEducational simulation or illustrative model outputCalculated from published equations with example inputs; not a measurement.
External partnerPerformed by a qualified external partnerWork a contract laboratory or other partner would carry out under agreement.
RiskRiskA known way a plan or result could fail, stated next to the claim it qualifies.

One chart never mixes categories without labeling each one. The six kinds in the heat map fold the ten labels: proposals, external-partner work, founder-reported experience and risks form one kind; regulation and agency guidance form another.

Research activity

The literature behind most library topics grew between 2015 and 2025; deep learning on natural products started from zero

MEDLINE records per year for each topic, 2015 and 2025Europe PMC counts
MEDLINE records per year for the research field behind each library page, 2015 and 2025, on a log scale, sorted by growth. Each row shows the 2015 and 2025 counts; the numbers are in the data table.1101001,000MEDLINE records per year (log scale; a count of 0 is drawn at 1); hollow = 2015, solid = 2025ChangeDeep learning on natural-product chemistryDeep learning on natural-product chemistry: 0 records in 2015Deep learning on natural-product chemistry: 65 records in 2025from 0Bayesian optimization and active learningBayesian optimization and active learning: 39 records in 2015Bayesian optimization and active learning: 311 records in 2025×8.0Life-cycle assessment of extractionLife-cycle assessment of extraction: 16 records in 2015Life-cycle assessment of extraction: 83 records in 2025×5.2Synergy and herb-drug interactionsSynergy and herb-drug interactions: 140 records in 2015Synergy and herb-drug interactions: 677 records in 2025×4.8Pharmacokinetics of botanicalsPharmacokinetics of botanicals: 124 records in 2015Pharmacokinetics of botanicals: 477 records in 2025×3.8DFT studies of plant phenolicsDFT studies of plant phenolics: 69 records in 2015DFT studies of plant phenolics: 253 records in 2025×3.7Bond dissociation enthalpy of antioxidantsBond dissociation enthalpy of antioxidants: 6 records in 2015Bond dissociation enthalpy of antioxidants: 20 records in 2025×3.3Solvent thermodynamics models (COSMO-RS,UNIFAC, NRTL)Solvent thermodynamics models (COSMO-RS, UNIFAC, NRTL): 26 records in 2015Solvent thermodynamics models (COSMO-RS, UNIFAC, NRTL): 83 records in 2025×3.2Response-surface optimization of extractionResponse-surface optimization of extraction: 264 records in 2015Response-surface optimization of extraction: 592 records in 2025×2.2Trade and supply of medicinal plantsTrade and supply of medicinal plants: 23 records in 2015Trade and supply of medicinal plants: 51 records in 2025×2.2Six Sigma, lean and SPC in manufacturingSix Sigma, lean and SPC in manufacturing: 14 records in 2015Six Sigma, lean and SPC in manufacturing: 26 records in 2025×1.9Adulteration and liver injury from supplementsAdulteration and liver injury from supplements: 66 records in 2015Adulteration and liver injury from supplements: 107 records in 2025×1.6Ethnobotany of medicinal plantsEthnobotany of medicinal plants: 108 records in 2015Ethnobotany of medicinal plants: 109 records in 2025×1.0
Source: Europe PMC REST API, query TITLE_ABS:(terms) AND SRC:MED AND PUB_YEAR:year, run October 24, 2026; search terms in the data table. A count is the number of matching MEDLINE records, not of studies on the page's exact subject.
The same topics year by year, 2000–2025, each row scaled to its own peak; select a year to sortEurope PMC counts
Same query and date as above. Narrow screens show every second or fifth year. Counts for the latest years can still rise as indexing continues.
Data table and search terms
MEDLINE records per year in Europe PMC whose title or abstract matches the search terms
Topic (page)2000200520102015202020242025CAGR 2015–2025Search terms in title or abstract
Solvent thermodynamics models (COSMO-RS, UNIFAC, NRTL)06102632698312.3%("COSMO-RS" OR "COSMO-SAC" OR UNIFAC OR NRTL) AND (solubility OR extraction OR solvent OR solvents)
DFT studies of plant phenolics015306911818225313.9%("density functional theory" OR DFT) AND (flavonoid OR flavonoids OR polyphenol OR polyphenols OR phenolic OR "natural product" OR "natural products")
Bond dissociation enthalpy of antioxidants131069142012.8%("bond dissociation enthalpy" OR "bond dissociation energy") AND (phenolic OR phenol OR antioxidant OR antioxidants OR flavonoid OR flavonoids)
Response-surface optimization of extraction1013692643875265928.4%("response surface methodology" OR "Box-Behnken" OR "central composite design" OR "design of experiments") AND extraction
Deep learning on natural-product chemistry000093765from zero("deep learning" OR "large language model" OR "foundation model" OR transformer) AND ("natural product" OR "natural products" OR phytochemical OR phytochemicals OR "medicinal plant" OR "medicinal plants")
Bayesian optimization and active learning59263910927431123.1%("Bayesian optimization" OR "Bayesian optimisation" OR "active learning") AND (extraction OR formulation OR chemistry OR process)
Pharmacokinetics of botanicals11435512418431547714.4%(pharmacokinetics OR pharmacokinetic) AND ("plant extract" OR "plant extracts" OR botanical OR herbal OR phytochemical OR phytochemicals OR "medicinal plant" OR "medicinal plants")
Synergy and herb-drug interactions17436414025938767717.1%(synergy OR synergistic OR "herb-drug interaction" OR "herb-drug interactions") AND ("plant extract" OR "plant extracts" OR botanical OR herbal OR phytochemical OR phytochemicals OR "medicinal plant" OR "medicinal plants")
Adulteration and liver injury from supplements41038661051281075.0%(adulteration OR adulterated OR "liver injury" OR hepatotoxicity) AND ("dietary supplement" OR "dietary supplements" OR "herbal supplement" OR "herbal supplements" OR "herbal medicine")
Six Sigma, lean and SPC in manufacturing3911141419266.4%("six sigma" OR "lean manufacturing" OR "statistical process control" OR "process capability") AND (pharmaceutical OR food OR manufacturing)
Life-cycle assessment of extraction03131629738317.9%("life cycle assessment" OR "life-cycle assessment" OR LCA) AND (extraction OR "plant extract" OR botanical OR biorefinery)
Ethnobotany of medicinal plants91728108104971090.1%("medicinal plant" OR "medicinal plants") AND (ethnobotany OR ethnobotanical)
Trade and supply of medicinal plants2410232246518.3%("medicinal plant" OR "medicinal plants" OR "herbal medicine" OR "herbal products") AND (trade OR "supply chain" OR harvesting OR "wild collection")
All pages

Every page in the library, with its figures, tools and evidence mix

Bar on each card: evidence labels on that pageVerified dataPeer-reviewedRegulation or guidanceThird-party estimateProposal, partner or riskSimulation or schematic
Molecular and phase science

Interactive science lab

Five calculators: extraction, creaming, freeze-drying, stability, resolution.

3 figures7 interactive
Molecular and phase science

Thermodynamics & COSMO-SAC

Phase diagrams, COSMO-RS and UNIFAC against measured data.

13 figures11 interactive
Molecular and phase science

Quantum chemistry

DFT surface charges and COSMO-SAC solvent screening.

13 figures9 interactive
Molecular and phase science

Ab initio reactivity

Computed O–H bond strengths of plant phenolics.

8 figures6 interactive
Optimization, data and AI

Large Botanical Model

A proposed multimodal model; none exists yet.

12 figures8 interactive
Optimization, data and AI

Botanical Intelligence

Hybrid models defined before any data exist.

10 figures3 interactive
Evidence, safety and lessons

Evidence & pharmacokinetics

Evidence ladder, bioavailability and herb–drug interactions.

8 figures3 interactive
Evidence, safety and lessons

Lessons learned

Documented failures and the controls each prompted.

12 figures3 interactive
Operations and sustainability

Operational excellence

SPC, capability, FMEA and FDA inspection data.

16 figures11 interactive
Operations and sustainability

Sustainability and LCA

Life-cycle assessment, solvent greenness, wild harvest.

14 figures4 interactive
Markets, trade and sourcing

Market data

Sales, growth rates and publisher estimates, sourced.

19 figures18 interactive
Markets, trade and sourcing

Competitive landscape

Named companies, from their own filings.

10 figures4 interactive
Markets, trade and sourcing

Global botanical atlas

Regional botanicals on a world map, with status.

10 figures5 interactive
Markets, trade and sourcing

Global trade data

Customs data on botanical raw materials.

14 figures13 interactive
Verification

Model register

Every calculator: equations, limits, verification.

0 figures
Six transport problems along one process chain, and the pages that treat eachPublished physics
Process chain from ground plant particle through extraction, emulsion, drying and stable powder to a delivery format, with the transport physics each step must control and the library pages that cover itGround plant particleExtractionEmulsion or colloidDryingStable powderDelivery formatPhysics to controlCovered onDiffusion out of theparticleExtraction andpurificationInteractive science labSolvent power;supercritical CO₂density;residual-solvent limitsExtraction andpurificationProcess engineeringand scale-upCreaming, flocculation,coalescence, OstwaldripeningColloid and emulsionscienceInteractive science labSpray drying andfreeze-drying; dryingcurvesDrying and particleengineeringProcess engineeringand scale-upGlass transition andwater activityDrying and particleengineeringInteractive science labLipid, self-emulsifying,colloidal, solid-statesystemsAdvanced ingredientdeliveryProcess chain from plant particle to delivery format, with the physics each step must controlGround plant particleDiffusion out of the particleCovered on: Extraction and purification; Interactivescience labExtractionSolvent power; supercritical CO₂ density; residual-solventlimitsCovered on: Extraction and purification; Processengineering and scale-upEmulsion or colloidCreaming, flocculation, coalescence, Ostwald ripeningCovered on: Colloid and emulsion science; Interactivescience labDryingSpray drying and freeze-drying; drying curvesCovered on: Drying and particle engineering; Processengineering and scale-upStable powderGlass transition and water activityCovered on: Drying and particle engineering; Interactivescience labDelivery formatLipid, self-emulsifying, colloidal, solid-state systemsCovered on: Advanced ingredient delivery
A generic sequence for orientation; not every product passes through every step. Topics as listed on the linked pages.
Models in the order they would have to earn their place; the large model comes lastProposed sequence
Three rungs of model complexity, from a published model reproduced exactly to a proposed large model that would come last, all resting on the same validation requirementsPublished model, reproduced exactlyA black cumin extraction model, its responsesurfaces and a live NSGA-II Pareto frontDesign space and multi-objective optimizationHybrid models, defined before any dataTarget variable, test splits by lot and botanical,baselines, calibration, stopping rules, model cardBotanical Intelligence: hybrid modelsLarge Botanical Model, lastA proposed multimodal model for identity andevidence; no model existsLarge Botanical ModelApplies to every rung: held-out validation, applicability domains, calibration and credibility assessmentComputational science and AIEach rung must earn its place against simpler methods before the next is attemptedThree rungs of model complexity on one validation base1 · Published model, reproduced exactlyA black cumin extraction model, its response surfacesand a live NSGA-II Pareto frontDesign space and multi-objective optimization2 · Hybrid models, defined before any dataTarget variable, test splits by lot and botanical, baselines,calibration, stopping rules, model cardBotanical Intelligence: hybrid models3 · Large Botanical Model, lastA proposed multimodal model for identity and evidence;no model existsLarge Botanical ModelApplies to every rung: held-out validation, applicabilitydomains, calibration and credibility assessmentComputational science and AIEach rung must earn its place against simpler methodsbefore the next is attempted
Order and requirements as stated on the linked pages. No EUTECNIQ model has been trained; the Large Botanical Model does not exist.

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